The cell surface adhesins of Mycobacterium tuberculosis
نویسندگان
چکیده
منابع مشابه
Improved surface culturing of Mycobacterium tuberculosis.
In studies on surface components of virulent mycobacteria, there is a continuous need for relatively large quantities of these organisms as produced in surface culture in Roux bottles. Achieving effective surface growth depends upon adequately seeding the surface of the liquid medium. A practice which may well have been employed even by Koch has been the transfer of a pellicle of "veil growth" ...
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Tuberculosis remains a major public health problem in both developing and developed countries. Drug-resistant tuberculosis is an increasing health problem and serious challenge to tuberculosis (TB) control programs. Information about the susceptibility pattern of Mycobacterium tuberculosis isolates against anti-tuberculosis drugs is an important aspect to TB control. The objectives of the s...
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BACKGROUND Vaccine-induced human antibodies to surface components of Haemophilus influenzae and Streptococcus pneumonia are correlated with protection. Monoclonal antibodies to surface components of Mycobacterium tuberculosis are also protective in animal models. We have characterized human antibodies that bind to the surface of live M. tuberculosis. METHODS Plasma from humans with latent tub...
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We report the crystal structure of the first prokaryotic aspartic proteinase-like domain identified in the genome of Mycobacterium tuberculosis. A search in the genomes of Mycobacterium species showed that the C-terminal domains of some of the PE family proteins contain two classic DT/SG motifs of aspartic proteinases with a low overall sequence similarity to HIV proteinase. The three-dimension...
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Using the phoA gene fusion methodology adapted to mycobacteria, several Mycobacterium tuberculosis DNA fragments encoding exported proteins were recently identified. In this paper, the molecular cloning, genomic positioning, nucleotide sequence determination and transcriptional start site mapping of a new M. tuberculosis gene, identified by this methodology, are reported. This gene was called e...
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ژورنال
عنوان ژورنال: Microbiological Research
سال: 2020
ISSN: 0944-5013
DOI: 10.1016/j.micres.2019.126392